Ask Acumen

Yuli Wu, MD

Vice President, Drug Safety & Pharmacovigilance

How long have you been with Acumen?

I joined Acumen in October 2023 and have been with the company for about 2.5 years.

What initially drew you to Acumen and our company’s mission?

The treatment of Alzheimer’s Disease (AD) is a significant unmet medical need. I believed it would be rewarding to collaborate with Acumen’s talented team, leveraging my medical safety expertise to contribute to the development of a novel treatment for AD.

How does your role contribute to the overall vision of the company?

As the head of Drug Safety & Pharmacovigilance, my role is to provide medical safety expertise and leadership in clinical trial safety, signal detection, safety evaluation, and risk management to ensure patient safety.

Which of Acumen’s four values (People, Integrity, Innovation, and Perseverance) resonates most with your work and role?

Integrity is the cornerstone of Drug Safety & Pharmacovigilance. As the head of this function, my role is to safeguard the patients who rely on us by ensuring that every safety report, signal assessment, and regulatory submission is handled with uncompromising integrity and technical excellence.

From your perspective, what sets our company apart in the field of Alzheimer’s research?

Our company distinguishes itself in the Alzheimer’s research landscape through a talented world-class team and the rigorous science underpinning our products. Sabirnetug is the first monoclonal antibody developed to selectively target toxic Aβ oligomers and is expected to provide superior cognitive efficiency and improved safety and tolerability.

What is a quote that is meaningful to you and why?

In Steve Jobs’ 2005 Stanford Commencement Address, he said: “Your work is going to fill a large part of your life, and the only way to be truly satisfied is to do what you believe is great work. And the only way to do great work is to love what you do.”  This quote reminds us that excellence grows from passion. When we genuinely enjoy our work, it transforms from a routine obligation into a source of fulfillment, where challenges are embraced as opportunities for growth.

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