Cynthia Lemere, PhD is an Associate Professor of Neurology in the Ann Romney Center for Neurologic Diseases at Brigham and Women’s Hospital and Harvard Medical School in Boston. Dr. Lemere’s research focuses on using the immune system therapeutically for the treatment of Alzheimer’s disease. Studies out of her lab explore the role of immune system proteins in Alzheimer’s disease and the clearance of amyloid-beta from the brain, as well as gaining a better understanding of the development and progression of Alzheimer’s disease in Down syndrome; identifying the risks of deep space radiation on the brain; and understanding the contributions of a disease-related, modified form of amyloid-beta, called pyroglutamate amyloid-beta, to Alzheimer’s disease and determining its value as a therapeutic target.
In 1997, Dr. Lemere started her own lab when she became an Assistant Professor of Neurology at Brigham and Women’s Hospital and Harvard Medical School. There, her interests shifted to include the role of inflammation and the immune system in Alzheimer’s disease. In 2004, she became an Associate Professor of Neurology at Brigham and Women’s Hospital and Harvard Medical School and since then, the majority of her work has focused on developing a safe and effective amyloid-beta vaccine for the prevention or treatment of Alzheimer’s disease.
Dr. Lemere serves on several national and international scientific advisory boards, including the ADPD Scientific Advisory Council, the Brightfocus Foundation Scientific Review Council, the National Alzheimer’s Association Medical and Scientific Advisory Council, and the DIAN-TU Therapeutic Evaluation Committee.